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Cell Factory Research Center

Cell Factory Research Center
The final objective is to develop cell factory that produce industrial materials with high efficiency and industrialization and based on microalgae and yeast, 1) development of microorganism cell factory through metabolic route redesigning, 2) establishment of highly efficient production system, 3) verification of in vitro, in vivo based cell activation and usability, 4) expansion of industrial ecosystem through the establishment of industrial base
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researchers and research statement
name research fields
Hee-Sik Kim
/ Associate Director
  • Development of cell factory through redesigning of microalgae metabolic route
  • Microalgae culture and analysis on the interaction of bacteria
  • Production of useful bio materials using microorganism fermentation process
Jung Hoon Sohn
/ Principal Researcher
  • Research on the recombined protein production system
  • Metabolic engineering of yeast based bio energy/chemical material production
Jae Wha Kim
/ Principal Researcher
  • Establishment of external factors that are involved in bio regulation and immunity activation related to disease and securing candidate materials through demonstration of efficacy
Chi-Yong Ahn
/ Principal Researcher
  • Environmental modeling regarding fresh water quality and the mass generation of cyanobacteria
  • Physiological ecological and molecular research on cyanobacteria and its toxicity
Hee-Mock Oh
/ Principal Researcher
  • Research on the physiological and ecological characteristics of microalgae and algal bloom control
  • Making optimized system for microalgae culture and production of bio diesel
Jeong-Woo Seo
/ Principal Researcher
(Concurrent Position)
  • Development of useful bio materials based on sea algae microorganism,
Bong Hyun Sung
/ Senior Researcher
  • Microorganism genomics, bio chemistry, artificial photosynthesis
Hyung Gwan Lee
/ Senior Researcher
  • Research on the classification of system based on microorganism molecular evolution
  • Metabolic redesigning of lipids and chromatophore of microalgae
Lee Yong Jae
/ Researcher
  • Genetic engineering of microorganisms, Protein engineering, Microbial fermentation
Bae Jung Hoon
/ Principal Technician
  • Yeast metabolic and production of recombined protein
research areas
  • Development of microalgae cell factory to produce photo aging control materials
  • Development of yeast cell factory to produce eco-friendly bio materials
  • Establishment of high-efficient production system for yeast and micro algae based bio materials
  • Analysis on the effectiveness and value of bio activity of bio materials
  • Establishment of the industrial foundation for bio materials for improvement and treatment of skin aging
  • Research on the controlling and monitoring of algal bloom
  • Production of yeast based recombined protein and application in industry
  • Industrialization of yeast originated glycolipid
    • Successfully industrializing bio natural emulgens and cosmetics materials through development of MEL: mannosylerythritol lipid biologically synthesized by Pseudozyma sp. and establishment of mass production of fermentation
  • Development of yeast recombined protein customized production technology (TFP technology)
    • Development and industrialization of high secretion of medicinal protein and industrial enzyme using GRAS yeast Saccharomyces cervisiae
  • Development of bio catalyst based eco-friendly bio diesel production technology
    • Development of bio diesel production technology utilizing low quality waste oil based on bio catalyst lipase and transfer of technology
  • Development of bio diesel production micro algae and optimized culture technology
    • Exploring high lipide algae based on physiology and ecology and designing optimized culture to secure micro algae biomass and development of molecular biological improvement technology based on omics.
  • Development of eco-friendly algal bloom and molecular monitoring technology
    • Development of technology that controls algal bloom eco friendly deterring mass expansion of cyanobacteria using ecological structure and function in water ecosystem and development of molecular monitoring technology based on molecular characteristics of cyanobacteria that causes algal bloom
Outstanding Papers
  • Hee-Sik Kim (Corresponding) Biotechnol. Adv. 34(1):14-29 (2016)
    • Algae-bacteria interactions: Evolution, ecology and emerging applications
  • Hee-Mock Oh (Corresponding) Biotechnol. Bioeng. 112(2): 288-296 (2015)
    • Simple processes for optimized growth and harvest of Ettlia sp. by pH control using CO2 and light irradiation.
  • Chi-Yong Ahn (Corresponding) Water Res. 68: 680-691 (2015)
    • Effects of photoperiod on nutrient removal, biomass production, and algal-bacterial population dynamics in lab-scale photobioreactors treating municipal wastewater
  • Jung-Hoon Sohn (Corresponding) Sci. Rep.-UK 5:12229 (2015)
    • An Efficient Genome-Wide Fusion Partner Screening System for Secretion of Recombinant Proteins in Yeast.
  • Jae Wha Kim (Corresponding) J. Cell. Biochem. 117:172-179 (2016)
    • PRDM1, a Tumor-Suppressor Gene, is Induced by Genkwadaphnin in Human Colon Cancer SW620 Cells
  • Bong Hyun Sung (First-author) ACS catal. 5: 5016-5025 (2015)
    • Recombinant Lipase Engineered with Amphipathic and Coiled-CoilPeptides.
  • Hyung-Gwan Lee (First-author) Phycologia 55(1):72-78 (2016)
    • Unique mitochondrial genome structure of the green algal strain YC001, with morphological observations