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Microbial Biotechnology Research Center

Microbial Biotechnology Research Center
Objectives
Development of useful bio materials (health care and biochemistry) and commercialization technology through research on microbial enzyme and metabolic function
  • Identification of useful microorganism function and understanding of its characteristics
  • Improvement of mibrobial enzyme and metabolic function
  • Development of commercialization process for microbial function
Researcher
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researchers and research statement
name research fields
Jae Jun Song
/ Associate Director
(Concurrent Position)
  • Exploration of useful enzymes by searching for data at high speed based on robot and development of technology for commercialization
  • Development of technology to establish genome library from unculturable rare microorganism
Jeong-Woo Seo
/ Principal Researcher
  • Development of useful bio materials based on sea algae microorganism,
Chul Ho Kim
/ Principal Researcher
  • Bio process, bio refinery, bio energy
Ohsuk Kwon
/ Principal Researcher
(Concurrent Position)
  • Microorganism molecular genetics and synthesis biology
Hee-Sik Kim
/ Principal Researcher
(Concurrent Position)
  • Production and harvesting microalgae biomass for new and renewable energy
  • Analysis on the interaction between microalgae and bacteria and identification of mechanism
  • Production of useful bio material using microorganism fermentation process
Seonghun Kim
/ Senior Researcher
  • Development of applied technology for materials related to sugar chain and carbohydrate
  • Development of technology that synthesize bio energy and chemical precursor based on sugar platform
Jong Hyun Choi
/ Senior Researcher
  • Development and utilization of smart microorganism through search for useful enzyme and metabolic pathway using high speed search system
  • Production of bio material through development of various tool boxes that can be applied to bio engineering based on system bio engineering
Minsoo Kim
/ Senior Researcher
  • Development of bio polymer fermentation technology
  • Development of sweetening from tangerine byproduct
Ji Young Kang
/ Senior Researcher
  • Production of polysaccharide-degrading enzymes
  • Production of protein for animal vaccine
Baek Rock Oh
/ Researcher
  • Biological process (fermentation)
  • Production of bio fuel and bio chemical
research areas
  • Development of High-throughput toolbox originated from metagenome for system metabolic engineering
    • Development of technology that explores new useful metabolic pathway/enzyme based on HTS
    • Development of customized industrial strain for producing various kinds of bio materials
  • Development of microbial material and commercialization technology
    • Development of aging control lipid (omega-3 PUFA derivatives)
    • Sugar compound material development for immune system improvement (glukan, Mannan saccharide, etc.)
    • Development of bio friendly material that can replace harmful chemical material (bio alcohol, organic acid)
Achievements
  • Development of high speed exploration technology by combining microbeads and flow cytometry
    • Development of new metabolic pathway, enzyme screening at high speed by linking single cell based microbead mass production and in vitro compartmentatlization method
  • Development of useful bio material originated from Thraustochytrid sea algae
    • Development of omega-3 PURA metaolome that controls aging
    • Sugar compound material development for immune system improvement
    • Development of technology utilizing mycobiont and oil byproduct (extraction and transformation of useful material)
  • Development of bio refinery technology to produce bio chemical material based on bio mass
    • Production of bio chemical material through microbial fermentation (propanediol, butanediol, isobutanol, adipic acid, etc.)
    • Development of bio ethanole production technology through fibroid material carbon source
Outstanding Papers
  • Jeong-Woo Seo (Corresponding) Bioproc Biosyst Eng. 36(7):959-963.
    • Production of lipids containing high levels of docosahexaenoic acid from empty palm fruit bunches by Aurantiochytrium sp. KRS101
  • Jeong-Woo Seo and Chul Ho Kim (Co-corresponding) Bioresour Technol. 130:719-24.
    • The production of 1,3-propanediol from mixtures of glycerol and glucose by a Klebsiella pneumoniae mutant deficient in carbon catabolite repression
  • Jong Hyun Choi and Jae Jun Song (Co-corresponding) Biotech. Bioeng. 112(4):822-826.
    • Enhancing Functional Expression of Heterologous Proteins Through Random Substitution of Genetic Codes in the 5’ Coding Region
  • Jong Hyun Choi and Jae Jun Song (Co-corresponding) Biotech. Bioeng. in press.
    • Itaconic acid production from glycerol using Escherichia coli harboring a random synonymous codon-substituted 5’-coding region variant of the cadA gene
  • Seonghun Kim and Chul Ho Kim (Co-corresponding) Renewable Energy. 54:150-5.
    • Bioethanol production using the sequential acid/alkali-pretreated empty palm fruit bunch fiber
  • Baek-Rock Oh Biotechnol Lett. 36:57-62
    • Production of 2-butanol from glycerol by a genetically-engineered Klebsiella pneumoniae strain