Current page location

Genome Editing Research Center

Genome Editing Research Center
Objectives
Research on gene function using genome editing technology
  • Development and upgrade of genome editing technology
  • Research on gene function and gene therapy using genome editing technology
  • Production of transformation mouse model using genome editing technology
Researcher
researchers and research statement
Name Research Fields
Yong-Sam Kim
(Associate Director)
  • Development of a new gene editing technology
  • Research on the advancement of a gene editing technology
Yong Sung Kim
  • Exploration of epigenetic target genes related to cancer and stem cell differentiation
  • Development of epigenetic gene editing technology for a target gene
Byoung-Mog Kwon
  • Exploration of genes related to diseases utilizing biochemical and chemical genomics and identification of the function, utilizing gene editing technology
Jeong-Heon Ko
  • Research on the function of glucide genes and development of glucide gene editing technologies
Namshin Kim
  • NGS-based Genome Platform by Assessment of Genome Variant and Genic Intolerance
  • Development of Genomic Prediction Algorithm & Software by Artificial Intelligence
  • Development of Open Source Platform for High-Density Genotyping Technologies
Seon-Young Kim
  • Research on the understanding of cancer in the human body through the functional genome approach
  • Bioinformatics and computational biology
Dae-Yeul Yu
  • Production of transformation mouse model and research on its function
In-Sun Chu
  • Biomedical informatics
Se-Joo Kim
  • Bioresource Information
Yoonkyung Kim
  • Biocompatible polymer, dendrimer, nano-medicine(diagnosis, drug delivery), organic/supramolecular/medicinal chemistry
Jeong Gu Kang
  • Development of method to regulate epigenetic target genes utilizing a gene editing technology
Jinhyuk Lee
  • Structural Proteomics
Bo Kyeng Hou
  • Bioresource information, Systems biology
research areas
  • Research on the upgrade of genome editing technology
    • Research on the improvement of efficiency for CRISPR/Cas9 and CRISPR/cpf1 genome editing technology
    • Establishment of target regulation system of genes related to stem cell, disease and aging
  • Development of human mimicking mouse model using saccharide genome editing technology
    • Selection of saccharide gene that causes differences of saccharide between human and mouse and development of mouse model with modification of the gene.
    • Verification of non clinical appropriateness of human mimicking mouse
  • Development of new genome editing technology
    • Development and verification of effectiveness for the 4th generation genome editing technology
  • Development of mouse model of diseases using animal transformation technology
  • Research on the mechanism of antioxidant enzyme in the cancer development process
  • Finding the biologically active mechanism of disordered protein and mechanism of causing disease
  • Design, synthesis, and application of new organic macromolecules or nano-sized compounds for the diagnosis and treatment of intractable diseases
Achievements
  • Induction of selective expression of target genes using genome editing technology
    • Development of gene expression regulation system based on TALEN targeting E-cadherin promoter
  • Development of epigenetic regulation method of target gene
    • Development and verification of technology that induces epigenetic transformation specific to a certain chromatin structure
  • Development of mouse model of various disease including liver and lung cancer
  • Finding the area of activated PreSMo of disordered protein for the first tie and spread the idea to the world
  • Development of new nano-sized dendritic compounds for diagnostic imaging of cancer and retinal diseases