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Biochemicals & Synthetic Biology Research Center

Development of diagnosis/sensing devices and synthetic biological tools through the convergence of Bio-Nano-Chemical technologies
- Development of novel proteins for diagnosis/sensing devices
- Development of synthetic biology-based genetic circuits for sensing and controlling cellular metabolism
- Construction of a biofab repository for designing and synthesizing customized proteins
researchers and research statement
Name |
Research Fields |
Seung-Goo Lee (Associate Director) |
- Synthetic biology, Protein engineering, Biomolecular imaging
|
Chul Ho Kim |
- Biorefinery and Bioenergy, Functional biomaterials, Bioprocess
|
Jung-Hoon Sohn |
- Yeast secretory production of recombinant proteins
- Yeast-based platform technology for bioenergy and biochemicals
- Lipase engineering for eco-friendly production of biodiesel
|
Doo-Byoung Oh |
- Protein therapeutics, Glycan analysis and remodeling
|
Heung-Chae Jung |
- Metabolic/enzyme engineering, Microbial physiology, Surface protein expression
|
Dae-Hee Lee |
- Synthetic biology, Metabolic engineering, Genome evolution and application
|
Sang Jick Kim |
- Phage-antibody library building, Production of protein medicine
|
Haseong Kim |
- Systems biology, Genetic circuit design
|
Soo-Jin Yeom |
- Protein/enzyme engineering, Synthetic Biology
|
Hyewon Lee |
- Bioimaging, Biosensors and Biochips
|
Bong Hyun Sung |
- Microbial genome engineering, enzyme engineering and artificial photosynthesis
|
- Systems biology
- Integrative analysis of mult-omics data and in silico modeling and simulation of biological networks
- Synthetic Biology
- Development of high-throughput enzyme screening system based on artificial genetic circuits
- Development of microbial cell factories implying intelligent control of cellular networks
- Synthetic biology-based development of high-value natural compounds
- Novel materials for Bioconvergence
- Design and synthesis of sensor proteins customized for antibodies (e.g. sugar chain, peptide, toxicity)
- Development of novel bioconvergence proteins of diagnosis and sensing through artificial evolution of enzymes

- Comprehensive understanding of whole-system of industrial microbes through integrative analyses of genome, transcriptome, proteome, phenome, and metablic/transcriptional networks
- Understanding of genome evolution and adaptation in a long-term experiment with Escherichia coli
- Development of microbial cell factories and analyses of signal transduction networks
- Development of platform technologies of intelligent genetic circuits and bioconvergence
- Development of GESS(Genetic Enzyme Screening System) sensing a trace of enzyme activity from single cell/colony
- GESS-based high-throughput screening and artificial protein evolution of cellulase, lipase, amidase, etc
- Characterization of biosynthetic pathways of novel enzymes for the production of pharmaceuticals, natural compounds, and chemicals
- Development of novel proteins for diagnosis/sensing devices
- Development of specific binding proteins for cytokine and chemicals through high-throughput screening of biomolecular interactions and its biosensor application
- Development of fluorescent probes for detection of fucosylated N-glycans
- Development of high sensitive FRET molecular sensor