Futuristic Animal Resource & Research Center (FARRC) has been established for contributing to the vitalization of future bio-industries, including new bio-drug discovery, xenotransplantation and regenerative medicine. Further, the center works to address national/social issues, such as artificial blood and foot-and-mouth disease by developing research support system that could be utilized across the government ministries, based on national mini-pig infrastructure that combines the world’s best resources, materials, technologies, instruments, facilities, and specialists.
Research Areas
Obtainment and standardization of specific pathogen free (SPF) mini-pig resources
Supply of mini-pig resources/materials/techniques/information
Industry/academia/research institute support
Establishment of research needs-customizing/leading infrastructure
The center has obtained mini-pigs through breeding and maintenance, under a stable SPF environment.
Derivation of research resources from SPF minipigs
Support industry/academia/research institute demands and establish somatic cell nuclear transfer methodsomatic cell lines were established from a variety of mini-pig tissues.
Establishment of transgenesis/cloning system in mini-pigs
Transgenic mini-pigs were successfully generated by the production of cloned embryos, embryo transfer into foster mothers, delivery by caesarian section and artificial nursing, indicating the successful establishment of the transgenesis/cloning system in mini-pigs.
Selected Publications
Abnormal gene expression in regular and aggregated somatic cell nuclear transfer placentas.
BMC Biotechnol. 17(1):34.
Bo Woong Sim (First)
Ganglioside GM3 induces cumulus cell apoptosis through inhibition of epidermal growth factor receptor-mediated PI3K/AKT signaling pathways during In vitro maturation of pig oocytes.
