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Introduction
  • National Primate Research Center (NPRC) was established as a major national non-human primate infrastructure to support industry/academia/research institute, including those involved in xenotransplantation, regenerative medicine, and new-drug discovery for incurable diseases.
Research Areas
  • Acquisition, propagation, and distribution of specific pathogen free (SPF) non-human primate resources
  • Standardization of the processes of handling and regulating lab requirements for non-human primate research
  • Xenotransplantation research
  • Regenerative medical research and applications
  • Pre-clinical efficacy assessments of newly developed drug candidates
  • Evaluation of immunogenicity and safety of vaccine candidates
  • Development of disease models
  • Genome research and the establishment of genomic database and support for animal biosafety level 3(ABL 3) research facilities
  • Collaboration and support for nationwide noninstitutional research involving non-human primates
Head
Investigator
Name Position Tel / Email Detail
Jae Won Huh Associate Director / Detail

Tel

043-240-6327

Email

huhjw@kribb.re.kr

Achievements
  • Procurement of SPF non-human primate resources, maintenance, breeding of healthy SPF animals, and pre-clinical evaluation of biomedical technologies
  • Transfer of non-human primate-related resources and techniques to national partners of industry/academia/research institute
  • Establishment of disease models using non-human primates
  • Collaboration with national and international research teams
Selected Publications
  • CRISPR diagnosis and therapeutics with single base pair precision.
    • Trends Mol Med. 26(3):337-350.
    • Seung Hwan Lee (First)
  • Transient Lymphopenia and Interstitial Pneumonia With Endotheliitis in SARS-CoV-2-Infected Macaques.
    • J Infect Dis. 13;222(10):1596-1600.
    • Jung Joo Hong (Corresponding)
  • Prediction-based highly sensitive CRISPR off-target validation using target-specific DNA enrichment.
    • Nat Commun. 17;11(1):3596.
    • Seung Hwan Lee (Corresponding)
  • Streptozotocin Induces Alzheimer's Disease-Like Pathology in Hippocampal Neuronal Cells via CDK5/Drp1-Mediated Mitochondrial Fragmentation.
    • Front Cell Neurosci. 4;14:235.
    • Youngjeon Lee (Corresponding)
  • A single mutation in the ACTR8 gene associated with lineage-specific expression in primates.
    • BMC Evol Biol. 5;20(1):66.
    • Jae-Won Huh (Corresponding)