BioProcess Engineering Center (BPEC) is a skilled division that provides engineering solutions for technical issues in biological processes.
Since 1995, the center plays a unique role in Korea’s industrial biotechnological R&D ecosystem, by transforming scientific proof of concepts into value propositions in the field, including the microbial fermentation, biotransformation, and downstream processing of biochemical materials. In addition, the center established research facilities for animal cell culture, to efficiently respond to the recent explosive growth in the biopharmaceutical industry. The center has been carrying out the mass production and commercialization of protein drugs using animal cells, while gaining more knowledge about advanced biotechnology. Nowadays, the center is providing a range of support services to strengthen domestic bio-industry capabilities, for example, it provides support for the industrialization of results obtained during research and equipment utilization, in addition to professional manpower training.
Research Areas
Microbial fermentation and scale-up research for biomaterials production
Mammalian cell culture for biopharmaceuticals production
Development of a new cell line for production of monoclonal antibodies by CHO cells
Process development of mammalian cells for biopharmaceuticals production
Microbial engineering for recombinant protein production
Yeast biotechnology for polymeric bio-monomer production from plant oil
Selected Publications
Characterization of the newly isolated ω-oxidizing yeast Candida sorbophila DS02 and its potential applications in long-chain dicarboxylic acid production.
Appl Microbiol Biotechnol. 101(16):6333-6342.
Hong-Weon Lee (Corresponding)
Enhanced performance of the methylerythritol phosphate pathway by manipulation of redox reactions relevant to IspC, IspG, and IspH.
J Biotechnol. 248:1-8.
Eui Sung Choi (Co-corresponding)
One-step purification of melittin derived from Apis mellifera bee venom.
J Microbiol Biotechnol. 27(1):84-91.
Eun Gyo Lee (Corresponding)
Complete genome sequence of the sulfur-oxidizing chemolithoautotrophic Sulfurovum lithotrophicum 42BKTT.
